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Mhd Riza Marjoni Pengarang Dewi Nofita Pengarang Noni Rahmi Pengarang Saifullah Pengarang Nurul Afifah Najla Pengarang

Arumanis is one of Indonesian mango varieties that have traditionally been used to prevent various noninfectious diseases such as diabetes, cancer, and other degenerative diseases. The active ingredients contained in Arumanis leaves (Mangifera indica L. Var. Arumanis) have the ability to stabilize free radicals which is one of the factors causing these diseases. Materials and Methods: In this study, the extract was used to validate the potential of this plant as a source of natural antioxidants. The antioxidant activity of the extract was expressed as inhibitory concentration (IC50), whereas total phenolic and flavonoid contents were each determined using the Folin–Ciocalteu method and Chang method. Results and Discussion: The results showed that Arumanis leaves (M. indica L. Var. Arumanis) had an IC50 value of 48.458 μg/mL. Total phenolic obtained was 1280 mg of gallic acid/g from the extracted compound, and the total flavonoid contents obtained was 1240.1 mg expressed in terms of quercetin equivalent. Conclusion: Research data showed that methanol extract of Arumanis leaves (M. indica L. Var. Arumanis) was significantly able to free radicals scavenging which correlated with high phenolic and flavonoid contents.